James McArdle, PhD – Head of CMC

Dr. Jim McArdle is a chemist and was Vice President of Isis/Ionis Corporation from 1999-2008. Due to his leadership experience at Ionis, and several nucleic acid therapeutics projects he oversaw at Archemix and as a consultant, he is a leading expert in ASO delivery, formulation, development and related regulatory filings. Dr. McArdle has over 37 years’ pharmaceutical experience in chemistry, manufacturing, and controls, with the last 22 years focused on synthetic oligonucleotides. He has deep technical expertise relating to ASO synthesis, analysis, formulation, development, and regulatory affairs.